Donatos Pepperoni Calzone

With a GLP-1 score of 42/100, Donatos Pepperoni Calzone is rated Caution. Its strongest attribute is Protein and lowest-scoring is Calories. Donatos Pepperoni Calzone is worth approaching carefully and may not suit everyone on GLP-1.

Donatos Pepperoni Calzone has 52g of protein — a high-protein option that's strong for muscle retention on GLP-1 medications, which can otherwise accelerate muscle loss.

With 51g of fat, Donatos Pepperoni Calzone carries a higher nausea risk for GLP-1 users, especially after a dose increase. If you want to try it, consider a smaller portion and eat slowly.

Donatos Pepperoni Calzone has 1120 calories, on the higher end. GLP-1 medications reduce appetite, so you may find you can't finish a full serving — consider sharing or saving half for later.

Donatos Pepperoni Calzone ranks 81st out of 87 items at Donatos by GLP-1 score. The top-scoring item is Donatos Chicken Caprese Entree Salad with Balsamic Vinaigrette at 79/100.